This policy brief explores the challenges of trade fragmentation and inequality in the global economy, focusing on the impact on low- and middle-income countries. It outlines policy solutions to reduce trade costs, invest in infrastructure, promote economic diversification, and strengthen global trade governance. Specific recommendations for the Fourth Conference on Financing for Development (FFD4) include financing for trade infrastructure, bridging the digital divide, improving access to finance, and reducing trade barriers to foster inclusive and sustainable development.